
Models of Disc Degeneration
What is the goal of the Study?
This Study aims to learn more about in-vitro models of disc degeneration. In this review paper, the authors sought a clinical perspective on the current state of in-vitro modelling related to the disruption, overloading…

Words and Diagnostic Labels of LBP Prognosis
Goal of the Study?
The goal of this study is to learn more about a patient's perception and expected outcome when a diagnosis is shared with them regarding their low back pain. In a recent paper published in the European Spine Journal[1.Public…

Cell Clustering in Disc Degeneration – Reparative Potential Within
Goal of the Study?
Learning how back pain develops and potentially advances in degenerative disc disease is critical. Back pain has profound socioeconomic costs worldwide. In this research paper[1.Cell clustering in intervertebral disc degeneration:…

Belly Up vs. Belly Down MRI | What are we missing? Prone MRI vs. Supine MRI in Low Back Pain Patients
Goal of the Study?
It is not uncommon to encounter remarkable pain patients with unremarkable MRI findings in clinical settings. Conventional MRI is done lying down, facing up (supine) in a recumbent and off-loading environment. This group…

Disk Degeneration Higher than Reported in the Youth at this Hospital
Goal of the Study?
The goal of this study[1.Magnetic resonance imaging findings among young adults with low back pain at Nsambya hospital] was to have a closer look at the younger population's lower back MRI findings. Most epidemiological investigations…

Tensile forces create spinal spurs | Biomechanical Evaluation of Spondylophyte Development
Goal of the Study?
Bone spurs that project off vertebral bodies (spondylophytes) are common. However, the causes of their development are somewhat curious. Are these vertebral spurs due to tensile (stretching/lengthening) forces, or are they…

Low Rate Loading Regenerated Degenerated Discs
Goal of the Study?
The regenerative potential of a degenerated disc has been questioned over the years. In this ISSLS prize-winning study[1.ISSLS Prize in Bioengineering Science 2022: low rate cyclic loading as a therapeutic strategy for intervertebral…

Mechanical Strain Accelerates Intervertebral Disc Degeneration Through Circadian Rhythm Disruption
Goal of the Study?
The intervertebral disc often plays a role in back pain. In this study[1.Excessive mechanical strain accelerates intervertebral disc degeneration by disrupting intrinsic circadian rhythm] researchers were curious about how…

Fundamentals of Intervertebral Disc Degeneration
Goal of the Study?
In this review article from the Annals of Weill Cornell Neurological Surgery[1.Fundamentals of Intervertebral Disc Degeneration] the authors’ goals were twofold: a) Cover the underlying pathophysiology and risk factors…