Loading the Spine
Modelling Disc Dynamics
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Models of Disc Degeneration

What is the goal of the Study? This Study aims to learn more about in-vitro models of disc degeneration. In this review paper, the authors sought a clinical perspective on the current state of in-vitro modelling related to the disruption, overloading…
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Words and Diagnostic Labels of LBP Prognosis

Goal of the Study? The goal of this study is to learn more about a patient's perception and expected outcome when a diagnosis is shared with them regarding their low back pain. In a recent paper published in the European Spine Journal[1.Public…
disk degeneration
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Disk Degeneration Higher than Reported in the Youth at this Hospital

Goal of the Study? The goal of this study[1.Magnetic resonance imaging findings among young adults with low back pain at Nsambya hospital] was to have a closer look at the younger population's lower back MRI findings. Most epidemiological investigations…
Intervertebral Disc Herniation
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Fibrotic alterations in human annulus fibrosus correlate with progression of intervertebral disc herniation

Goal of the Study? In this histological analysis article from the Arthritis Research and Therapy Journal [1. Fibrotic Alterations In Human Annulus Fibrosus Correlate With Progression Of Intervertebral Disc Herniation] the authors’ goal was…
three dimensional modelling
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Three-dimensional Modelling Dynamic Diurnal Disc Changes – Posterior and Anterior Look with MRI

Goal of the Study? We all know that LBP is a worldwide problem. Yet, the disc and its functional relationship to low back pain are poorly understood. These researchers worked to use MRI and three-dimensional modelling to measure in-vivo shape…
Vacuum PhenomenonDynamic Disc Designs Corp.
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Vacuum Phenomenon – What is it and can it tell us anything about the dynamics of the spine?

Goal of the Study? Intradiscal vacuum phenomenon is a commonly observed radiological finding in the spine but not much is known about its pathophysiology. A recent paper was published in The European Spine Journal[1.Advanced disc degeneration,…
Degenerative Intervertebral Disc
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Correlation Between Proteolytic Enzymes and Micro Angiogenesis in Degenerative Intervertebral Disc Nucleus

Goal of the Study? In this case-control study from the Journal of Investigative Surgery [1. Correlation Between Proteolytic Enzymes and Micro Angiogenesis in Degenerative Intervertebral Disc Nucleus] the authors’ goal was to determine if…
Disc Nucleus
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Correlation Between Proteolytic Enzymes and Microangiogenesis in Degenerative Intervertebral Disc Nucleus

Goal of the review? The goal of the article, [1. Correlation Between Proteolytic Enzymes and Microangiogenesis in Degenerative Intervertebral Disc Nucleus] explores the molecular level of intervertebral disc degeneration. Specifically, the…