Disc height loss is a common thread in the work-up of spine related pain. Our models showcase disc height loss in a dynamic way to help convey load dynamics and changes over the life-cycle of a human as well as diurnal variations.

Loading the Spine
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Loading the Spine in MRI

Loading the spine and the differences seen in MRI
Modelling Disc Dynamics
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Models of Disc Degeneration

What is the goal of the Study? This Study aims to learn more about in-vitro models of disc degeneration. In this review paper, the authors sought a clinical perspective on the current state of in-vitro modelling related to the disruption, overloading…
lumbar instability
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Can MRI findings predict lumbar instability?

Goal of the Study? Vertebral slippage (spondylolisthesis) can occur in the ageing spine. In listhesis, one vertebra is either forward or backwards relative to its adjacent vertebral partner in the vertebral column. In this research study [1.Magnetic…
Disc Height Narrowing
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Natural Disc Height Narrowing Does Not Help with Cervical Spondylolisthesis

Goal of the Study? Disc height narrowing is thought to incur stabilization over time as discs dry out and age. However, in this study[1.Disc Height Narrowing Could Not Stabilize the Mobility at the Level of Cervical Spondylolisthesis: A Retrospective…
disk degeneration
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Disk Degeneration Higher than Reported in the Youth at this Hospital

Goal of the Study? The goal of this study[1.Magnetic resonance imaging findings among young adults with low back pain at Nsambya hospital] was to have a closer look at the younger population's lower back MRI findings. Most epidemiological investigations…
Spondylophyte osteophyte
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Tensile forces create spinal spurs | Biomechanical Evaluation of Spondylophyte Development

Goal of the Study? Bone spurs that project off vertebral bodies (spondylophytes) are common. However, the causes of their development are somewhat curious. Are these vertebral spurs due to tensile (stretching/lengthening) forces, or are they…
Regenerated
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Low Rate Loading Regenerated Degenerated Discs

Goal of the Study? The regenerative potential of a degenerated disc has been questioned over the years. In this ISSLS prize-winning study[1.ISSLS Prize in Bioengineering Science 2022: low rate cyclic loading as a therapeutic strategy for intervertebral…
Intervertebral Disc Herniation
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Fibrotic alterations in human annulus fibrosus correlate with progression of intervertebral disc herniation

Goal of the Study? In this histological analysis article from the Arthritis Research and Therapy Journal [1. Fibrotic Alterations In Human Annulus Fibrosus Correlate With Progression Of Intervertebral Disc Herniation] the authors’ goal was…