
Low Rate Loading Regenerated Degenerated Discs
Goal of the Study?
The regenerative potential of a degenerated disc has been questioned over the years. In this ISSLS prize-winning study[1.ISSLS Prize in Bioengineering Science 2022: low rate cyclic loading as a therapeutic strategy for intervertebral…

Fibrotic alterations in human annulus fibrosus correlate with progression of intervertebral disc herniation
Goal of the Study?
In this histological analysis article from the Arthritis Research and Therapy Journal [1. Fibrotic Alterations In Human Annulus Fibrosus Correlate With Progression Of Intervertebral Disc Herniation] the authors’ goal was…

Early Modic Changes in Paediatric Low Back Pain Patients – ISSLS Prize Winner
Goal of the Study?
Low back pain is the number one disabling condition in the world. In 1988, eight years after the first clinical MRI was conducted in Scotland by Francis Smith MD, Michael Modic MD identified unique MRI findings associated…

Vacuum Phenomenon – What is it and can it tell us anything about the dynamics of the spine?
Goal of the Study?
Intradiscal vacuum phenomenon is a commonly observed radiological finding in the spine but not much is known about its pathophysiology. A recent paper was published in The European Spine Journal[1.Advanced disc degeneration,…

Clinical and MRI findings in degenerative lumbar spinal stenosis
Goal of the Study?
In this cross-sectional study from the European Spine Journal [1. Clinical and MRI findings in lumbar spinal stenosis: baseline data from the NORDSTEN study] the authors’ primary goal was to describe the relationship…

Effect of overload on changes in mechanical and structural properties of disc biomechanics
Goal of the Study?
In this primary research study from the Biomechanics and Modeling in Mechanobiology Journal[1.Effect of overload on changes in mechanical and structural properties of the intervertebral disc] the authors analyzed structural…

Extruded disc herniations are experienced earlier by inactive young people in the high-tech gaming era.
Goal of the article?
The goal of this study, [1. Extruded disc herniations are experienced earlier by inactive young people in the high-tech gaming era] is to examine why there is an increasing incidence of disc herniation in young people.
Why…

Correlation Between Proteolytic Enzymes and Microangiogenesis in Degenerative Intervertebral Disc Nucleus
Goal of the review?
The goal of the article, [1. Correlation Between Proteolytic Enzymes and Microangiogenesis in Degenerative Intervertebral Disc Nucleus] explores the molecular level of intervertebral disc degeneration. Specifically, the…

Dynamic Sitting Exercise vs. McKenzie Prone Press-Up (Low back pain and quality of life)
The Dynamic Sitting Exercise (DSE)
Life can be busy. And with this busyness, people often do not have the time for lower back pain exercises. In 2010, Jerome Fryer (the owner and developer of Dynamic Disc Designs Corp.) set out to measure a…